Punzalan M, Hyden G. The role of physical therapy and occupational therapy in the rehabilitation of pediatric and adolescent patients with osteosarcoma.
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Eur J Surg Oncol. P16INK4a overexpression and survival in osteosarcoma patients: a meta analysis.
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The hazards of the biopsy, revisited. Members of the Musculoskeletal Tumor Society. Craig FS. Vertebral-body biopsy. Log In.
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Sign Up It's Free! Register Log In. No Results. If you log out, you will be required to enter your username and password the next time you visit. Log out Cancel. Share Email Print Feedback Close. Sections Osteosarcoma. Background Osteosarcoma is the most common malignant bone tumor. Chest radiograph of patient with osteosarcoma who died from pulmonary metastatic disease. Note the presence of a pneumothorax as well as radiodense bone-forming metastatic lesions.
View Media Gallery. Pathophysiology Osteosarcoma is a bone tumor and can occur in any bone, usually in the extremities of long bones near metaphyseal growth plates. Etiology The exact cause of osteosarcoma is unknown. Epidemiology In the United States, the incidence of osteosarcoma is 3. Whites — 3. Age years — 2.
Age years — 8. Prognosis The present understanding of outcome and prognosis for osteosarcoma is driven by certain serum markers, clinical staging, and histologic response to chemotherapeutic agents. Clinical Presentation. Media Gallery. Clinical appearance of a teenager who presented with osteosarcoma of the proximal humerus same patient as in the following images.
Osteosarcoma - an overview | ScienceDirect Topics
Note the impressive swelling throughout the deltoid region, as well as the disuse atrophy of the pectoral musculature. Radiographic appearance plain radiograph of a proximal humeral osteosarcoma same patient as previous image.
Note the radiodense matrix of the intramedullary portion of the lesion, as well as the soft-tissue extension and aggressive periosteal reaction. Intense radionuclide uptake of the proximal humerus is noted on a bone scan same patient as previous 2 images. A comparison bone scan of the involved shoulder right image with the uninvolved shoulder left image same patient as previous 3 images. Magnetic resonance image appearance T1-weighted image of osteosarcoma of the proximal humerus same patient as previous 4 images.
Note the dramatic tumor extension into the adjacent soft-tissue regions.
Related background history of bone cancer
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